On a PCB I'm working with, I have analog feedbacks running through op-amps into a 3.3V microcontroller. Thus, signals outside 0-3.3V are useless, and potentially dangerous to the microcontroller. The op amps have +-15V rails, because those rails were available and convenient. However, that means it's possible for my op amp to destroy my microcontroller by railing out positive. In perfect operation this should never happen, but I'm considering edge cases. To improve reliability, I'm considering connecting my op amps to +3.3V and -15V.
Is there any reason I should not run an op amp off asymmetrical voltage rails?
Obviously, railing out negative could also destroy the processor. I'm only considering the positive-rail case at the moment.
