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I am planning to use polydimethylsiloxane (PDMS) to create a phantom for mimicking tissue for imaging. For this, I plan on using SYLGARD® 184, which is a viscous liquid. When adding other components to it, air bubbles will be introduced.

I have learned that one way (available to me) to remove bubbles / de-gas the solution is by using a vacuum pump to create negative pressure. What negative pressure is sufficient to remove the air from the gel-like solution?

Air
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Nazar
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1 Answers1

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15-30 mins under any vacuum pump will be fine. If there are any air bubbles still there at the surface I recommend to burst it with pressurized air gun. Make sure that your vacuum chamber lid is sealed well. Some time it is useful to use vacuum grease to achieve that.

Nabeel Kadhim Abbood
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