Check first you are talking about OpenLiteSpeed, not LiteSpeed (Enterprise).
As mentioned in "Switching Between OLS and LSWS on DirectAdmin":
On DirectAdmin, you can either run LiteSpeed Enterprise, or OpenLiteSpeed, but you cannot run both at the same time.
Then double-check your configuration files and reload process, assuming your Apache .htaccess is set.
Confirm that OpenLiteSpeed is actively running:
sudo /usr/local/lsws/bin/lswsctrl status
# Or try to restart it
sudo /usr/local/lsws/bin/lswsctrl restart
Make sure the configuration files are correctly set up and not empty:
cat /usr/local/lsws/conf/httpd_config.conf
Look for error messages that might indicate the problem:
cat /usr/local/lsws/logs/error.log
Verify if OpenLiteSpeed is listening on the default HTTP/HTTPS ports (80/443):
sudo netstat -tulnp | grep 'OpenLiteSpeed'